Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043722 | 0.79 | BACE1 (0.43) | BACE1BACE2CTSD | |
| SCHEMBL6043432 | 0.78 | BACE1 (0.54) | BACE1BACE2CTSD | |
| SCHEMBL6044654 | 0.77 | BACE1 (0.39) | BACE1 | |
| SCHEMBL6043902 | 0.74 | BACE1 (0.43) | BACE1BACE2CTSD | |
| SCHEMBL6044292 | 0.73 | BACE1 (0.45) | BACE1BACE2CTSD | |
| SCHEMBL6044082 | 0.73 | BACE1 (0.43) | BACE1BACE2CTSD | |
| SCHEMBL3352804 | 0.72 | BACE1 (0.61) | BACE1BACE2CTSD | |
| SCHEMBL3352797 | 0.72 | BACE1 (0.61) | BACE1BACE2CTSD | |
| SCHEMBL6044454 | 0.71 | BACE1 (0.42) | BACE1BACE2CTSD | |
| SCHEMBL6043285 | 0.71 | BACE1 (0.41) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430032-A2 | SUBSTITUTED AMIDES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Elan Pharmaceuticals, Inc. (US) | 2004-06-23 | — | — | EP | claimed |
| WO-2003027068-A2 | SUBSTITUTED AMINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | ELAN PHARMACEUTICALS, INC. (US) | 2003-04-03 | — | — | WO | claimed |