Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607609 | 1.00 | HPGD (0.36) | HPGDCHEK1KDM4EMAPTALDH1A1 | |
| SCHEMBL6611068 | 0.85 | HPGD (0.40) | HPGDCHEK1KDM4EMAPTALDH1A1 | |
| SCHEMBL6611074 | 0.85 | HPGD (0.40) | HPGDCHEK1KDM4EMAPTALDH1A1 | |
| SCHEMBL6609082 | 0.83 | MAPT (0.38) | HPGDKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL6609086 | 0.83 | MAPT (0.38) | HPGDKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL6605803 | 0.83 | PDE4D (0.44) | HPGDCHEK1KDM4EMAPTALDH1A1 | |
| SCHEMBL6605809 | 0.83 | PDE4D (0.44) | HPGDCHEK1KDM4EMAPTALDH1A1 | |
| SCHEMBL8398005 | 0.82 | PDE4D (0.40) | HPGDKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL8398010 | 0.82 | PDE4D (0.40) | HPGDKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL6609522 | 0.82 | MAPT (0.37) | HPGDKDM4EMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |