Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 18/20 | 0.67 |
| ▸ | CCR5 | P51681 | 2/20 | 0.67 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106036 | 0.91 | CCR4 (0.74) | CCR4CCR5 | |
| SCHEMBL5098574 | 0.85 | CCR4 (0.70) | CCR4CCR5 | |
| SCHEMBL5105223 | 0.82 | CCR4 (1.00) | CCR4CCR5EDNRA | |
| SCHEMBL6039005 | 0.80 | CCR4 (0.73) | CCR4CCR5EDNRA | |
| SCHEMBL5103230 | 0.76 | CCR4 (1.00) | CCR4CCR5EDNRA | |
| SCHEMBL6181343 | 0.76 | CCR4 (0.54) | CCR4CCR5 | |
| SCHEMBL5105251 | 0.76 | CCR4 (0.78) | CCR4CCR5 | |
| SCHEMBL6038863 | 0.74 | CCR4 (0.66) | CCR4CCR5EDNRA | |
| SCHEMBL5103307 | 0.74 | CCR4 (0.78) | CCR4CCR5EDNRA | |
| SCHEMBL5105666 | 0.74 | CCR4 (0.82) | CCR4CCR5EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458715-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051870-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |