Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 18/20 | 0.67 |
| ▸ | CCR5 | P51681 | 2/20 | 0.64 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5102857 | 0.84 | CCR4 (0.69) | CCR4CCR5EDNRA | |
| SCHEMBL5111839 | 0.82 | CCR4 (1.00) | CCR4CCR5EDNRA | |
| SCHEMBL5103230 | 0.82 | CCR4 (1.00) | CCR4CCR5EDNRA | |
| SCHEMBL5105223 | 0.80 | CCR4 (1.00) | CCR4CCR5EDNRA | |
| SCHEMBL6038522 | 0.78 | CCR4 (0.69) | CCR4CCR5EDNRA | |
| SCHEMBL6039005 | 0.75 | CCR4 (0.73) | CCR4CCR5EDNRA | |
| SCHEMBL5105251 | 0.74 | CCR4 (0.78) | CCR4CCR5 | |
| SCHEMBL5105623 | 0.73 | CCR4 (0.72) | CCR4CCR5EDNRA | |
| SCHEMBL5105666 | 0.72 | CCR4 (0.82) | CCR4CCR5EDNRA | |
| SCHEMBL5106036 | 0.72 | CCR4 (0.74) | CCR4CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458715-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | claimed |
| WO-2003051870-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | claimed |