Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518574 | 0.87 | KDM4E (0.58) | ALDH1A1KDM4EAGTR1RAB9AKMT2A | |
| SCHEMBL6610969 | 0.87 | KDM4E (0.54) | ALDH1A1KDM4EAGTR1RAB9AKMT2A | |
| SCHEMBL11771339 | 0.84 | MAPT (0.56) | ALDH1A1KDM4EKMT2APOLBSMN1; SMN2 | |
| SCHEMBL9742572 | 0.84 | TSHR (0.61) | ALDH1A1KDM4EKMT2AHPGDHTT | |
| SCHEMBL5807040 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EAGTR1RAB9AKMT2A | |
| SCHEMBL4354505 | 0.83 | KDM4E (0.50) | ALDH1A1KDM4EAGTR1RAB9AKMT2A | |
| SCHEMBL7528637 | 0.82 | KDM4E (0.71) | ALDH1A1KDM4EKMT2AHPGDPOLB | |
| SCHEMBL4716443 | 0.82 | MEN1 (0.52) | ALDH1A1KDM4EAGTR1RAB9AKMT2A | |
| SCHEMBL7860463 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4EAGTR1RAB9AKMT2A | |
| SCHEMBL6653449 | 0.81 | MAPK13 (0.51) | ALDH1A1KDM4ERAB9AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114815-B1 | Process to prepare taxol | UPJOHN CO (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1352899-A1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-1352900-A1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-0912504-B1 | Oxazolidine ester | UPJOHN CO (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6307064-B1 | PHENYLISOSERINE ESTER OF SILYLATED BACCATIN III | PHARMACIA & UPJOHN COMPANY | 2001-10-23 | — | — | US | disclosed |
| EP-1114815-A2 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6177573-B1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY | 2001-01-23 | — | — | US | disclosed |
| US-6057452-A | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY | 2000-05-02 | — | — | US | disclosed |