Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789697 | 0.79 | MAPT (0.50) | GAAMAPTALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL2255782 | 0.79 | MAPT (0.50) | GAAMAPTALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1726909 | 0.76 | GAA (0.46) | GAAMAPTALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL21145451 | 0.76 | GAA (0.46) | GAAMAPTALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL2904681 | 0.76 | GAA (0.46) | GAAMAPT | |
| SCHEMBL1285713 | 0.76 | MAPT (0.46) | GAAMAPTALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL20338456 | 0.76 | MAPT (0.42) | GAAMAPT | |
| Hydrochloric Acid SCHEMBL6991456 | 0.74 | MAPT (0.41) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9293762 | 0.73 | GAA (0.43) | GAAMAPT | |
| SCHEMBL2125224 | 0.73 | GAA (0.43) | GAAMAPTALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933212-B | Novel combination and use | HELPERBY THERAPEUTICS LTD | 2015-07-22 | — | — | CN | disclosed |
| CN-101795688-B | Application of 4- (pyrrolidine-1-yl) quinoline compound in preparation of medicine for killing clinically latent microorganisms | HELPERBY THERAPEUTICS LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-101594866-B | Topical formulations | HELPERBY THERAPEUTICS LTD. (GB) | 2014-10-22 | — | — | CN | disclosed |
| CN-101351203-B | Application of pyrroloquinoline compound in killing clinically latent microorganisms | HELPERBY THERAPEUTICS LTD | 2013-12-04 | — | — | CN | disclosed |
| EP-1432701-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003031436-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. (CH) | 2003-04-17 | — | — | WO | disclosed |