SCHEMBL6608213

SCHEMBL6608213

CCN(CCN1CCCCC1)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL5224183 0.97 F10 (0.78) F10
SCHEMBL5225712 0.91 F10 (1.00) F10
SCHEMBL5222660 0.91 F10 (1.00) F10
SCHEMBL5230134 0.90 F10 (1.00) F10
Formic Acid SCHEMBL5228218 0.90 F10 (0.79) F10
SCHEMBL5223988 0.90 F10 (0.89) F10
SCHEMBL5227377 0.90 F10 (0.89) F10
SCHEMBL5224197 0.88 F10 (0.86) F10
Formic Acid SCHEMBL5228248 0.88 F10 (0.94) F10
SCHEMBL5226543 0.87 F10 (0.87) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444201-A1 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2004-08-11 EP disclosed
WO-2003043981-A1 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2003-05-30 WO disclosed