Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610236 | 1.00 | CYP2D6 (0.49) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL6612649 | 1.00 | CYP2D6 (0.49) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL2074391 | 0.78 | CYP2D6 (0.45) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL11291790 | 0.77 | CYP2D6 (0.53) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL18305517 | 0.77 | CYP2D6 (0.41) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL18305515 | 0.77 | CYP2D6 (0.41) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL18313666 | 0.75 | FLT3 (0.48) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL178528 | 0.75 | CYP2D6 (0.50) | CYP2D6HIF1AMAOBMEN1NPC1 | |
| SCHEMBL8158780 | 0.75 | FLT3 (0.48) | CYP2D6HIF1AMAOBTAS1R3TAS1R1 | |
| SCHEMBL18305555 | 0.74 | KMT2A (0.53) | MAOBMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458719-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-22 | — | — | EP | claimed |
| WO-2003053971-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-03 | — | — | WO | claimed |
| EP-1458719-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053971-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |