Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409520 | 0.81 | GSK3B (0.39) | GSK3BKDRERCC5FEN1ALDH1A1 | |
| SCHEMBL2987114 | 0.79 | GSK3B (0.62) | GSK3BDAO | |
| SCHEMBL1985851 | 0.77 | GSK3B (0.70) | POLBTDP1GSK3BALDH1A1HPGD | |
| SCHEMBL17955228 | 0.77 | TDP1 (0.51) | POLBTDP1GSK3BERCC5FEN1 | |
| SCHEMBL4140001 | 0.77 | DAO (0.59) | POLBTDP1GSK3BALDH1A1HPGD | |
| SCHEMBL3042810 | 0.76 | — | — | |
| SCHEMBL15221207 | 0.76 | — | — | |
| SCHEMBL13078179 | 0.75 | POLB (0.58) | POLBTDP1GSK3BALDH1A1HPGD | |
| SCHEMBL847050 | 0.75 | GSK3B (0.68) | POLBTDP1GSK3BALDH1A1HPGD | |
| SCHEMBL5737861 | 0.75 | HDAC3 (0.58) | POLBTDP1ALDH1A1HPGDCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853205-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | UNIVERSITY OF CONNECTICUT | 2012-02-23 | — | — | US | disclosed |
| EP-2398323-A1 | NOVEL HETERO PYRROLE ANALOGS ACTING ON CANNAPINOID RECEPTORS | University of Connecticut (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010104488-A1 | NOVEL HETERO PYRROLE ANALOGS ACTING ON CANNAPINOID RECEPTORS | UNIVERSITY OF CONNECTICUT (US) | 2010-09-16 | — | — | WO | disclosed |
| EP-1978023-A1 | Pyridazines as fungicides | Bayer CropScience Aktiengesellschaft (DE) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | CNR1, CNR2, CBR3 | POLB 3827/4885TDP1 2759/4885GSK3B 3263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.