Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609021 | 1.00 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6610544 | 0.92 | PDE4D (0.39) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6610539 | 0.92 | PDE4D (0.39) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6606525 | 0.89 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6606521 | 0.89 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6604955 | 0.84 | NPC1 (0.43) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6604946 | 0.84 | NPC1 (0.43) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6609752 | 0.84 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6609749 | 0.84 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL6608404 | 0.81 | PDE4D (0.40) | PDE4APDE4BPDE4CPDE4DL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |