Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492514 | 0.87 | PDE5A (0.55) | PDE5A | |
| SCHEMBL7079147 | 0.85 | PDE5A (0.53) | PDE5A | |
| SCHEMBL4535697 | 0.82 | PDE5A (0.53) | PDE5A | |
| SCHEMBL6615462 | 0.81 | PDE5A (0.54) | PDE5A | |
| SCHEMBL7149186 | 0.81 | PDE5A (0.54) | PDE5A | |
| SCHEMBL1327213 | 0.78 | PDE5A (0.60) | PDE5A | |
| SCHEMBL6609839 | 0.78 | PDE5A (0.56) | PDE5A | |
| SCHEMBL7154977 | 0.77 | PDE5A (0.52) | PDE5A | |
| SCHEMBL6412972 | 0.75 | PDE5A (0.70) | PDE5A | |
| SCHEMBL7154398 | 0.74 | PDE5A (0.61) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458679-A2 | PYRROLIDINE DERIVATIVES AS PROSTAGLANDIN MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053923-A2 | PYRROLIDINE DERIVATIVES AS PROSTAGLANDIN MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-07-03 | — | — | WO | disclosed |