Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 11/20 | 0.64 |
| ▸ | PTGER3 | P43115 | 10/20 | 0.64 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612898 | 1.00 | PTGER4 (0.64) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL12298847 | 0.91 | PTGER4 (0.64) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL12298846 | 0.86 | PTGER4 (0.73) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL14261759 | 0.86 | PTGER4 (0.73) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL14579896 | 0.84 | PTGER4 (0.56) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5213643 | 0.84 | PTGER4 (0.73) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5213647 | 0.84 | PTGER4 (0.73) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5213650 | 0.84 | PTGER4 (0.73) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5213653 | 0.84 | PTGER4 (0.73) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL14268700 | 0.82 | PTGER4 (0.53) | PTGER4PTGER2PTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408961-A1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003007941-A1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-01-30 | — | — | WO | disclosed |