Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.69 |
| ▸ | PPARA | Q07869 | 6/20 | 0.69 |
| ▸ | PPARG | P37231 | 4/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219007 | 0.89 | PPARD (0.72) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5217826 | 0.85 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL5215930 | 0.85 | PPARD (0.70) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5215936 | 0.85 | PPARD (0.70) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5216218 | 0.85 | PPARD (0.70) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5219186 | 0.83 | PPARD (0.65) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5221878 | 0.83 | PPARD (0.65) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5219192 | 0.83 | PPARD (0.65) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5218333 | 0.82 | PPARD (0.57) | PPARDPPARAPPARGFFAR1FFAR4 | |
| SCHEMBL6238901 | 0.82 | PPARD (1.00) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480640-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | claimed |
| WO-2003072100-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | claimed |
| EP-1480640-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072100-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |