SCHEMBL6613993

SCHEMBL6613993

O=C1C(NS(=O)(=O)/C=C/c2ccc(Cl)s2)CCN1c1ccc(-c2ccncc2Cl)cc1F

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6362993 1.00 F10 (0.72) F10
SCHEMBL6362996 1.00 F10 (0.72) F10
SCHEMBL6362353 0.83 F10 (0.85) F10
SCHEMBL6362348 0.83 F10 (0.85) F10
SCHEMBL6362004 0.83 F10 (1.00) F10
SCHEMBL6362008 0.83 F10 (1.00) F10
SCHEMBL6362336 0.83 F10 (0.77) F10
SCHEMBL6362335 0.83 F10 (0.77) F10
SCHEMBL6362751 0.82 F10 (0.86) F10
SCHEMBL6362750 0.82 F10 (0.86) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456172-A1 PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2004-09-15 EP disclosed
WO-2003053925-A1 PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2003-07-03 WO disclosed