SCHEMBL6614243

CCOc1ccc([C@H]2O[C@H](CC(=O)O)C(=O)N(CC(C)(C)C)c3ccc(Cl)cc32)c(OC)c1.COc1cccc([C@H]2O[C@H](CC(=O)NCCc3occc3C(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC

nearest known ligand 0.66

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	FDFT1	P37268	18/20	0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4104265	0.91	FDFT1 (0.77)	FDFT1
SCHEMBL7249492	0.91	FDFT1 (0.77)	FDFT1
SCHEMBL7253088	0.86	FDFT1 (0.75)	FDFT1
SCHEMBL7250147	0.86	FDFT1 (0.75)	FDFT1
SCHEMBL7254090	0.85	FDFT1 (0.69)	FDFT1
SCHEMBL7254087	0.85	FDFT1 (0.66)	FDFT1
SCHEMBL7255468	0.85	FDFT1 (0.67)	FDFT1
SCHEMBL7254093	0.82	FDFT1 (0.77)	FDFT1
SCHEMBL7085630	0.81	FDFT1 (0.79)	FDFT1
SCHEMBL4935340	0.81	FDFT1 (0.75)	FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1407782-A1	PREVENTIVES/REMEDIES FOR ORGAN FUNCTIONAL DISORDERS AND ORGAN DYSFUNCTION	Takeda Chemical Industries, Ltd. (JP)	2004-04-14	—	—	EP	disclosed