Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.55 |
| ▸ | FNTB | P49356 | 14/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364392 | 0.88 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL3500795 | 0.85 | FNTA (0.53) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL6614560 | 0.85 | FNTA (0.57) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3501377 | 0.85 | FNTA (0.57) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3500156 | 0.81 | FNTA (0.61) | FNTAFNTBALDH1A1LMNAP2RX7 | |
| SCHEMBL3499873 | 0.81 | FNTA (0.70) | FNTAFNTBALDH1A1LMNA | |
| SCHEMBL3502917 | 0.81 | FNTA (0.55) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3499785 | 0.81 | FNTA (0.55) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3501162 | 0.81 | FNTA (0.56) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3499709 | 0.81 | FNTA (0.54) | FNTAFNTBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | claimed |
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-0892797-A4 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL MYERS SQUIBB CO (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |
| EP-0892797-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030992-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |