Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 11/20 | 0.38 |
| ▸ | PPARA | Q07869 | 11/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220200 | 0.87 | FFAR1 (0.42) | PPARDPPARGPPARAFFAR1DRD4 | |
| SCHEMBL6615068 | 0.86 | PPARD (0.43) | PPARDPPARGPPARA | |
| SCHEMBL5218871 | 0.86 | FFAR1 (0.46) | PPARDPPARGPPARAFFAR1DRD4 | |
| SCHEMBL5850720 | 0.81 | FFAR1 (0.47) | PPARDPPARGPPARAFFAR1DRD4 | |
| SCHEMBL5852086 | 0.81 | PPARG (0.49) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL5850594 | 0.80 | FFAR1 (0.50) | PPARDPPARGPPARAFFAR1DRD4 | |
| SCHEMBL5850650 | 0.79 | FFAR1 (0.46) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL5850592 | 0.77 | PPARG (0.44) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL5850617 | 0.77 | PPARD (0.46) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL5850600 | 0.77 | FFAR4 (0.46) | PPARDPPARGPPARAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480640-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072100-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |