Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 1/20 | 0.43 |
| ▸ | SDHA | P31040 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712803 | 1.00 | F10 (0.47) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7712596 | 0.92 | F10 (0.47) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7712593 | 0.92 | F10 (0.47) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7710525 | 0.92 | F10 (0.47) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7710529 | 0.92 | F10 (0.47) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7704335 | 0.90 | F10 (0.46) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7704340 | 0.90 | F10 (0.46) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7709983 | 0.89 | F10 (0.45) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7704165 | 0.89 | F10 (0.47) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7704169 | 0.89 | F10 (0.47) | F10ITGB3ITGA2BPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | claimed |
| EP-1451164-A2 | AMIDE DERIVATIVES HAVING IMPROVED SOLUBILITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003006440-A2 | AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |