Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362456 | 1.00 | F10 (0.79) | F10 | |
| SCHEMBL6366482 | 0.88 | F10 (1.00) | F10 | |
| SCHEMBL6362334 | 0.88 | F10 (1.00) | F10 | |
| SCHEMBL6366101 | 0.87 | F10 (0.82) | F10 | |
| SCHEMBL6613889 | 0.86 | F10 (0.72) | F10 | |
| SCHEMBL6361712 | 0.86 | F10 (0.72) | F10 | |
| SCHEMBL6359974 | 0.85 | F10 (0.83) | F10 | |
| SCHEMBL6361999 | 0.85 | F10 (1.00) | F10 | |
| SCHEMBL6365741 | 0.85 | F10 (0.75) | F10 | |
| SCHEMBL6361345 | 0.84 | F10 (0.72) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456172-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053925-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-07-03 | — | — | WO | disclosed |