Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.71 |
| ▸ | PPARA | Q07869 | 5/20 | 0.71 |
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680872 | 0.91 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL5218966 | 0.87 | PPARD (0.71) | PPARDPPARAPPARG | |
| SCHEMBL6613722 | 0.86 | PPARG (0.74) | PPARDPPARAPPARG | |
| SCHEMBL4680724 | 0.83 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL6238213 | 0.83 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL5217676 | 0.83 | PPARD (0.66) | PPARDPPARAPPARGPTPN1 | |
| SCHEMBL6613647 | 0.79 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL5102109 | 0.79 | PPARG (0.80) | PPARDPPARAPPARG | |
| SCHEMBL4676727 | 0.78 | PPARG (0.67) | PPARDPPARAPPARGPTPN1 | |
| SCHEMBL5125457 | 0.78 | PPARA (0.66) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480640-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072100-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |