Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.64 |
| ▸ | FNTB | P49356 | 17/20 | 0.64 |
| ▸ | HRAS | P01112 | 1/20 | 0.64 |
| ▸ | KRAS | P01116 | 1/20 | 0.64 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bms-214662 SCHEMBL29454371 | 0.93 | FNTA (0.74) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL134854 | 0.93 | FNTA (0.74) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL134853 | 0.93 | FNTA (0.74) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3501155 | 0.88 | FNTA (0.63) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL22050803 | 0.86 | FNTA (0.86) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3500141 | 0.84 | FNTA (0.54) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499614 | 0.84 | FNTA (0.54) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499615 | 0.84 | FNTA (0.54) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3501297 | 0.84 | FNTA (0.54) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3498230 | 0.84 | FNTA (0.54) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892797-A4 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL MYERS SQUIBB CO (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0892797-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030992-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |