Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6637476 | 0.82 | DEPTOR (0.47) | DEPTORRAPGEF4NPC1RAB9AL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL6616054 | 0.79 | DEPTOR (0.38) | DEPTORRAPGEF4NPC1RAB9ATAAR1 | |
| SCHEMBL922290 | 0.76 | DEPTOR (0.47) | DEPTORRAPGEF4NPC1RAB9AL3MBTL1 | |
| SCHEMBL922291 | 0.76 | DEPTOR (0.47) | DEPTORRAPGEF4NPC1RAB9AL3MBTL1 | |
| SCHEMBL921557 | 0.75 | DEPTOR (0.48) | DEPTORRAPGEF4NPC1RAB9ATAAR1 | |
| SCHEMBL921556 | 0.75 | DEPTOR (0.48) | DEPTORRAPGEF4NPC1RAB9ATAAR1 | |
| Ammonia Solution, Strong SCHEMBL6618697 | 0.67 | MAPT (0.37) | NPC1RAB9AROCK2SMN1; SMN2ALDH1A1 | |
| SCHEMBL921896 | 0.65 | DEPTOR (0.46) | DEPTORRAPGEF4NPC1RAB9AL3MBTL1 | |
| SCHEMBL921897 | 0.65 | DEPTOR (0.46) | DEPTORRAPGEF4NPC1RAB9AL3MBTL1 | |
| SCHEMBL921503 | 0.64 | DEPTOR (0.44) | DEPTORL3MBTL1ABCG2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450791-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | Kinetek Pharmaceuticals, Inc. (CA) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045379-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-06-05 | — | — | WO | disclosed |