⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511856 | 0.76 | — | — | |
| SCHEMBL6820197 | 0.75 | — | — | |
| SCHEMBL5160748 | 0.75 | — | — | |
| SCHEMBL10466461 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL4729202 | 0.73 | — | — | |
| SCHEMBL7403169 | 0.69 | — | — | |
| SCHEMBL20220936 | 0.67 | — | — | |
| SCHEMBL14428097 | 0.67 | — | — | |
| SCHEMBL4334350 | 0.67 | — | — | |
| SCHEMBL8645497 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12336991-B2 | Factor XIIA inhibitors | UNIVERSITY OF LEEDS (GB) | 2025-06-24 | — | — | US | disclosed |
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
| EP-3773555-A1 | FACTOR XIIA INHIBITORS | University of Leeds (GB) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019186164-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2019-10-03 | — | — | WO | disclosed |
| EP-0985664-B1 | Method of producing pyrrolidine derivatives | TORAY FINECHEMICALS CO LTD (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6479668-B1 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-6130338-A | OXIDATING THE CORRESPONDING 3-PYRROLINE COMPOUND TO GIVE AN EPOXYPYRROLIDINE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0985664-A2 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0036584-A2 | Chelating ion exchanger based organic polymer and process for its preparation | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1981-09-30 | — | — | EP | disclosed |
| US-4251541-A | ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1981-02-17 | — | — | US | disclosed |