Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618114 | 0.89 | UTS2R (0.32) | ALDH1A1LMNAMAPTCA12CA1 | |
| Water SCHEMBL8623502 | 0.87 | KDM4C (0.38) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL8626608 | 0.85 | KDM6B (0.41) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL6618893 | 0.83 | LATS1 (0.40) | LMNA | |
| SCHEMBL6619663 | 0.83 | LATS1 (0.40) | LMNA | |
| SCHEMBL8623804 | 0.82 | KDM6B (0.40) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL4264934 | 0.78 | LATS1 (0.40) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL8626480 | 0.77 | CA12 (0.36) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL7083730 | 0.76 | KDM6B (0.44) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL8717642 | 0.75 | GAA (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877748-B1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | UNIV LIEGE (BE) | 2004-11-03 | — | — | EP | disclosed |
| US-5792764-A | ENDOCRINE DISORDERS ESPECIALLY AS A K(ATP)-CHANNEL MODULATOR | NOVO NORDISK A/S (DK) | 1998-08-11 | — | — | US | disclosed |