Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 3/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603969 | 0.91 | MAPK14 (0.62) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL6605456 | 0.87 | MAPK14 (0.69) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL6604303 | 0.86 | MAPK14 (0.68) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL6629040 | 0.83 | MAPK14 (0.63) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL4856672 | 0.82 | MAPK14 (0.70) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL4855098 | 0.81 | MAPK14 (0.77) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL4857965 | 0.80 | MAPK14 (0.67) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL4856374 | 0.80 | MAPK14 (0.72) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL6605075 | 0.80 | MAPK14 (0.68) | MAPK14MAPK11LCKCSF1RKDR | |
| SCHEMBL4861229 | 0.79 | MAPK14 (0.84) | MAPK14MAPK11LCKCSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436269-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033482-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-04-24 | — | — | WO | disclosed |