SCHEMBL6619464

CCCS(=O)(=O)N1Cc2cc(C#N)ccc2N(Cc2c[nH]cn2)C[C@@H]1[C@H](C)c1ccccc1.C[C@H](c1ccccc1)[C@H]1CN(Cc2c[nH]cn2)c2ccc(C#N)cc2CN1S(=O)(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	20/20	0.51

▸	FNTB	P49356	20/20	0.51

▸	HRAS	P01112	1/20	0.39

▸	KRAS	P01116	1/20	0.39

▸	PGGT1B	P53609	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6615866	1.00	FNTA (0.51)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3499847	0.96	FNTA (0.54)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3501129	0.96	FNTA (0.54)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3501644	0.96	FNTA (0.54)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3501127	0.96	FNTA (0.54)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3501541	0.96	FNTA (0.54)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3499852	0.96	FNTA (0.54)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3501813	0.94	FNTA (0.52)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3499372	0.94	FNTA (0.52)	FNTAFNTBHRASKRASPGGT1B
SCHEMBL3499283	0.94	FNTA (0.52)	FNTAFNTBHRASKRASPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0892797-A4	INHIBITORS OF FARNESYL PROTEIN TRANSFERASE	BRISTOL MYERS SQUIBB CO (US)	2004-10-20	—	—	EP	claimed
EP-0892797-A1	INHIBITORS OF FARNESYL PROTEIN TRANSFERASE	BRISTOL-MYERS SQUIBB COMPANY (US)	1999-01-27	—	—	EP	claimed
WO-1997030992-A1	INHIBITORS OF FARNESYL PROTEIN TRANSFERASE	BRISTOL-MYERS SQUIBB COMPANY (US)	1997-08-28	—	—	WO	claimed