Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620892 | 0.99 | CA1 (0.35) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL5364385 | 0.81 | KDM4E (0.40) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL5359312 | 0.79 | KDM4E (0.41) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL9358766 | 0.76 | KDM4E (0.43) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL27593283 | 0.74 | KDM4E (0.37) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL27593324 | 0.70 | KDM4E (0.39) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL5666036 | 0.66 | CA1 (0.44) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL29713976 | 0.66 | SMN1; SMN2 (0.49) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL27188910 | 0.66 | SMN1; SMN2 (0.49) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL13988029 | 0.65 | KDM4E (0.45) | CA1CA2CA7CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181294-B1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2004-03-31 | — | — | EP | disclosed |
| EP-1181294-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | Sanochemia Pharmazeutika Aktiengesellschaft (AT) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001074820-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) | 2001-10-11 | — | — | WO | disclosed |