Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.69 |
| ▸ | CX3CR1 | P49238 | 3/20 | 0.65 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842397 | 0.87 | CXCR2 (0.77) | CXCR2CX3CR1HTR1B | |
| Hydrochloric Acid SCHEMBL841595 | 0.86 | CXCR2 (0.76) | CXCR2CX3CR1HTR1B | |
| SCHEMBL842350 | 0.84 | CXCR2 (0.80) | CXCR2CX3CR1HTR1B | |
| SCHEMBL842874 | 0.83 | CXCR2 (0.68) | CXCR2CX3CR1HTR1B | |
| SCHEMBL5036023 | 0.82 | CXCR2 (0.70) | CXCR2CX3CR1HTR1B | |
| SCHEMBL842296 | 0.82 | CXCR2 (0.72) | CXCR2CX3CR1HTR1B | |
| SCHEMBL841838 | 0.82 | CXCR2 (0.83) | CXCR2CX3CR1HTR1B | |
| SCHEMBL841899 | 0.82 | CXCR2 (1.00) | CXCR2CX3CR1HTR1B | |
| SCHEMBL13140053 | 0.81 | CXCR2 (0.70) | CXCR2CX3CR1HTR1B | |
| SCHEMBL841616 | 0.81 | CXCR2 (0.98) | CXCR2CX3CR1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222195-B1 | NOVEL THIAZOLO(4,5-D)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LTD (GB) | 2004-01-14 | — | — | EP | claimed |