Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.57 |
| ▸ | FNTB | P49356 | 14/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633343 | 0.89 | FNTA (0.56) | FNTAFNTBBRD4 | |
| SCHEMBL6614995 | 0.89 | FNTA (0.56) | FNTAFNTBBRD4 | |
| SCHEMBL6635226 | 0.82 | FNTA (0.43) | FNTAFNTBBRD4 | |
| SCHEMBL6614821 | 0.82 | FNTA (0.41) | FNTAFNTBBRD4KMT2A | |
| SCHEMBL6619615 | 0.81 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL6635340 | 0.81 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL6619564 | 0.79 | FNTA (0.60) | FNTAFNTBKMT2A | |
| SCHEMBL6616053 | 0.78 | FNTA (0.45) | FNTAFNTBBRD4KMT2A | |
| SCHEMBL6616628 | 0.77 | FNTA (0.40) | FNTAFNTBBRD4 | |
| SCHEMBL6637318 | 0.76 | FNTA (0.56) | FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-0892797-A4 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL MYERS SQUIBB CO (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |
| EP-0892797-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030992-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |