Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.63 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.58 |
| ▸ | IDH1 | O75874 | 13/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325709 | 0.88 | AVPR2 (0.70) | AVPR2AVPR1AIDH1 | |
| SCHEMBL6614607 | 0.86 | AVPR2 (0.69) | AVPR2AVPR1AIDH1 | |
| SCHEMBL6615584 | 0.86 | AVPR2 (0.68) | AVPR2AVPR1AIDH1 | |
| SCHEMBL6616064 | 0.84 | AVPR2 (0.71) | AVPR2AVPR1AIDH1 | |
| SCHEMBL7317124 | 0.84 | AVPR2 (0.80) | AVPR2AVPR1AIDH1 | |
| SCHEMBL7320422 | 0.82 | AVPR2 (0.81) | AVPR2AVPR1AIDH1 | |
| SCHEMBL7949083 | 0.82 | AVPR2 (0.65) | AVPR2AVPR1AIDH1 | |
| SCHEMBL7334645 | 0.78 | AVPR2 (0.49) | AVPR2AVPR1A | |
| SCHEMBL27486147 | 0.78 | IDH1 (0.73) | IDH1 | |
| SCHEMBL7312662 | 0.77 | AVPR2 (1.00) | AVPR2AVPR1AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1272110-A | Tricyclic vasopressin agonists | AMERICAN HOME PROD (US) | 2000-11-01 | — | — | CN | claimed |
| EP-1000059-B1 | TRICYCLIC VASOPRESSIN AGONISTS | WYETH CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| CN-1162429-C | Tricyclic vasopressin agonists | — | 2004-08-18 | — | — | CN | disclosed |
| EP-1149096-B1 | TRICYCLIC PYRIDINE N-OXIDES VASOPRESSIN AGONISTS | WYETH CORP (US) | 2002-12-18 | — | — | EP | disclosed |
| CN-1347415-A | Tricyclic pyridine N-oxide vasopressin agonists | AMERICAN HOME PROD (US) | 2002-05-01 | — | — | CN | disclosed |
| US-6235900-B1 | Tricyclic pyridine N-oxides vasopressin agonists | AMERICAN HOME PRODUCTS CORPORATION | 2001-05-22 | — | — | US | disclosed |
| US-6194407-B1 | INCONTINENCE | AMERICAN HOME PRODUCTS CORPORATION | 2001-02-27 | — | — | US | disclosed |
| CN-1272110-A | Tricyclic vasopressin agonists | AMERICAN HOME PROD (US) | 2000-11-01 | — | — | CN | disclosed |
| US-6090803-A | ANTIDIABETIC AGENTS; INCONTINENCE | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-18 | — | — | US | disclosed |