Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.59 |
| ▸ | CCR3 | P51677 | 20/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737424 | 0.89 | HRH1 (0.60) | HRH1CCR3KCNH2 | |
| SCHEMBL3948076 | 0.85 | HRH1 (0.59) | HRH1CCR3KCNH2 | |
| SCHEMBL3938852 | 0.74 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL6242779 | 0.74 | HRH1 (0.72) | HRH1CCR3KCNH2 | |
| SCHEMBL5191226 | 0.74 | HRH1 (0.74) | HRH1CCR3KCNH2 | |
| SCHEMBL5190415 | 0.74 | HRH1 (0.74) | HRH1CCR3KCNH2 | |
| SCHEMBL4616813 | 0.74 | HRH1 (0.75) | HRH1CCR3KCNH2 | |
| SCHEMBL180334 | 0.73 | HRH1 (0.61) | HRH1CCR3KCNH2 | |
| Hydrochloric Acid SCHEMBL5189821 | 0.73 | HRH1 (0.72) | HRH1CCR3KCNH2 | |
| SCHEMBL4140781 | 0.73 | HRH1 (0.64) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487793-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078395-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-09-25 | — | — | WO | disclosed |