Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963382 | 0.90 | KCNH2 (0.47) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6620218 | 0.90 | KCNH2 (0.47) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6620975 | 0.89 | MEN1 (0.52) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6623149 | 0.87 | KDM4E (0.47) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6618869 | 0.86 | KCNH2 (0.52) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6619788 | 0.86 | KDM4E (0.45) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6622620 | 0.85 | KMT2A (0.50) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6622531 | 0.85 | POLB (0.48) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6619543 | 0.85 | MEN1 (0.53) | ALDH1A1KDM4EKCNH2KMT2AMEN1 | |
| SCHEMBL6622630 | 0.85 | MEN1 (0.53) | ALDH1A1KDM4EKCNH2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047695-B1 | NOVEL BISPIDINE ANTIARRHYTHMIC COMPOUNDS | ASTRAZENECA AB (SE) | 2004-03-17 | — | — | EP | disclosed |
| US-6291475-B1 | 3,7-DIAZABICYCLO(3.3.1)NONANE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |