Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809946 | 1.00 | — | — | |
| SCHEMBL17510806 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL7871012 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL958325 | 1.00 | — | — | |
| SCHEMBL890685 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL11359275 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL497990 | 0.97 | — | — | |
| SCHEMBL1567812 | 0.87 | — | — | |
| SCHEMBL7555214 | 0.78 | TSHR (0.55) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL3235111 | 0.78 | TSHR (0.55) | TSHRTHRBEP300FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104364257-A | TREATMENT OF PANCREATIC AND RELATED CANCERS WITH 5-ACYL-6,7-DIHYDROTHIENO[3,2-c]PYRIDINES | SLOAN KETTERING INST CANCER | 2015-02-18 | — | — | CN | disclosed |
| EP-1433787-A1 | 1,2,3-Thiadiazole derivatives, plant disease controller and method for using them | Nihon Nohyaku Co., Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6348460-B1 | TREATMENT OF PLANT DISEASES | NIHON NOHYAKU CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-0987257-A1 | 1,2,3-THIADIAZOLE DERIVATIVES, PLANT DISEASE CONTROLLING AGENT, AND METHOD FOR USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |