Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626429 | 0.91 | HTT (0.38) | HTTPTK2BCYP11B1CYP11B2HTR2A | |
| Hydrochloric Acid SCHEMBL8221158 | 0.90 | HTT (0.37) | HTTPTK2BCYP11B1CYP11B2HTR2A | |
| SCHEMBL6623725 | 0.89 | HTT (0.36) | HTTPTK2BCYP11B1CYP11B2 | |
| SCHEMBL6623857 | 0.88 | HTT (0.38) | HTTPTK2BHTR2AHTR2CKCNH2 | |
| SCHEMBL6623107 | 0.86 | HTT (0.35) | HTTPTK2BCYP11B1CYP11B2 | |
| SCHEMBL6624969 | 0.85 | CYP11B1 (0.43) | HTTPTK2BCYP11B1CYP11B2HTR2A | |
| SCHEMBL6623511 | 0.84 | HTT (0.36) | HTTPTK2B | |
| Hydrochloric Acid SCHEMBL6625955 | 0.83 | PARP1 (0.40) | HTTPTK2B | |
| SCHEMBL6624473 | 0.81 | MAPT (0.36) | HTTPTK2B | |
| SCHEMBL6623975 | 0.79 | PARP1 (0.39) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |