Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222282 | 1.00 | F10 (0.70) | F10 | |
| SCHEMBL5223564 | 0.97 | F10 (0.71) | F10 | |
| SCHEMBL5222319 | 0.90 | F10 (0.73) | F10 | |
| SCHEMBL6416601 | 0.90 | F10 (0.83) | F10 | |
| SCHEMBL5223325 | 0.90 | F10 (0.83) | F10 | |
| SCHEMBL5223685 | 0.90 | F10 (0.73) | F10 | |
| SCHEMBL5223642 | 0.86 | F10 (0.74) | F10 | |
| SCHEMBL6622749 | 0.85 | F10 (0.72) | F10 | |
| SCHEMBL5223928 | 0.84 | F10 (0.81) | F10 | |
| SCHEMBL5223987 | 0.83 | F10 (0.79) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444201-A1 | 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003043981-A1 | 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-05-30 | — | — | WO | disclosed |