SCHEMBL6623487

SCHEMBL6623487

CS(=O)(=O)N1Cc2cc(Br)ccc2N(Cc2cccnc2)C[C@H]1Cc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.74
FNTB P49356 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6623492 1.00 FNTA (0.74) FNTAFNTB
SCHEMBL6621701 0.91 FNTA (0.73) FNTAFNTB
SCHEMBL6621705 0.91 FNTA (0.73) FNTAFNTB
SCHEMBL7674417 0.87 FNTA (0.57) FNTAFNTB
SCHEMBL7674424 0.87 FNTA (0.57) FNTAFNTB
SCHEMBL3502098 0.86 FNTA (0.61) FNTAFNTB
SCHEMBL6624912 0.86 FNTA (0.70) FNTAFNTB
SCHEMBL6624919 0.86 FNTA (0.70) FNTAFNTB
SCHEMBL7673718 0.86 FNTA (0.55) FNTAFNTB
SCHEMBL7673712 0.86 FNTA (0.55) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1027042-A4 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE BRISTOL MYERS SQUIBB CO (US) 2004-08-18 EP claimed
US-6458783-B1 INHIBITION OF FARNESYL TRANSFERASE, WHICH IS AN ENZYME INVOLVED IN RAS ONCOGENE EXPRESSION, IS EFFECTED BY COMPOUNDS OF THE FORMULAS OF BENODIAZEPINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY 2002-10-01 US claimed
EP-1027042-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE BRISTOL-MYERS SQUIBB COMPANY (US) 2000-08-16 EP claimed
WO-1999018951-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE BRISTOL-MYERS SQUIBB COMPANY (US) 1999-04-22 WO claimed
US-6458783-B1 INHIBITION OF FARNESYL TRANSFERASE, WHICH IS AN ENZYME INVOLVED IN RAS ONCOGENE EXPRESSION, IS EFFECTED BY COMPOUNDS OF THE FORMULAS OF BENODIAZEPINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY 2002-10-01 US disclosed
WO-2001081322-A1 NON-IMIDAZOLE BENZODIAZEPINE INHIBITORS OF FARNESYL PROTEIN TRANSFERASE BRISTOL-MYERS SQUIBB COMPANY (US) 2001-11-01 WO disclosed