Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | UPP1 | Q16831 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204181 | 0.86 | KDM4E (0.45) | PLATKDM4EKDM5AKDM4DPOLB | |
| SCHEMBL6624656 | 0.78 | KDM4E (0.46) | PLATKDM4EKDM5APOLBHTT | |
| SCHEMBL16046861 | 0.77 | KDM5A (0.46) | PLATKDM4EKDM5AKDM4DPOLB | |
| SCHEMBL16046600 | 0.76 | KDM5A (0.43) | PLATKDM4EKDM5AKDM4DPOLB | |
| SCHEMBL16048043 | 0.75 | KDM5A (0.50) | PLATKDM4EKDM5AKDM4DPOLB | |
| SCHEMBL16046669 | 0.74 | KDM5A (0.48) | PLATKDM4EKDM5AKDM4DPOLB | |
| SCHEMBL18159119 | 0.73 | KDM5A (0.53) | PLATKDM4EKDM5AKDM4DPOLB | |
| SCHEMBL16046987 | 0.73 | KDM5A (0.56) | PLATKDM4EKDM5AKDM4DPOLB | |
| SCHEMBL16047853 | 0.73 | KDM5A (0.37) | PLATKDM4EKDM5AKDM4DHSD17B10 | |
| SCHEMBL17547884 | 0.72 | KDM5A (0.40) | PLATKDM4EKDM5AKDM4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976754-B1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEM IND INC (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-6329382-B1 | TREATMENT OF RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0976754-A1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |