Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 7/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1339972 | 0.78 | ALPI (0.52) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL3198336 | 0.78 | ALPI (0.52) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| Leucine SCHEMBL11019376 | 0.78 | SLC7A5 (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| Leucine SCHEMBL11019375 | 0.78 | SLC7A5 (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| Cysteine SCHEMBL4970300 | 0.77 | PTGS1 (0.52) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| Dl-Phenylalanine SCHEMBL27397102 | 0.76 | SLC7A5 (0.69) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL15971325 | 0.75 | SLC1A3 (0.81) | SLC1A3SLC1A2SLC1A1LTA4H | |
| SCHEMBL8984826 | 0.75 | SLC1A3 (0.81) | SLC1A3SLC1A2SLC1A1LTA4H | |
| SCHEMBL2313979 | 0.75 | SLC1A3 (0.81) | SLC1A3SLC1A2SLC1A1LTA4H | |
| SCHEMBL29151574 | 0.74 | KMT2A (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385831-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083651-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-10-24 | — | — | WO | disclosed |