Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.53 |
| ▸ | FLT1 | P17948 | 11/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 6/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622760 | 0.95 | EGFR (0.55) | EGFRFLT1KDRSYKVCP | |
| SCHEMBL6304865 | 0.93 | EGFR (0.54) | EGFRFLT1KDRSYKVCP | |
| SCHEMBL6310600 | 0.93 | EGFR (0.54) | EGFRFLT1KDRSYKVCP | |
| SCHEMBL6626442 | 0.92 | EGFR (0.53) | EGFRFLT1KDRSYK | |
| SCHEMBL6302087 | 0.91 | EGFR (0.53) | EGFRFLT1KDRSYK | |
| SCHEMBL6304401 | 0.91 | EGFR (0.57) | EGFRFLT1KDRSYKVCP | |
| SCHEMBL6625762 | 0.91 | EGFR (0.53) | EGFRFLT1SYK | |
| SCHEMBL6305020 | 0.90 | EGFR (0.62) | EGFRFLT1KDRSYK | |
| SCHEMBL6624984 | 0.88 | EGFR (0.50) | EGFRFLT1KDRSYKGRM4 | |
| SCHEMBL6623534 | 0.88 | EGFR (0.51) | EGFRFLT1KDRSYKVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287001-B1 | THIOPHENE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PROD INC (US) | 2004-09-29 | — | — | EP | disclosed |