Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493708 | 0.90 | PDE2A (0.46) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5493713 | 0.90 | PDE2A (0.46) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| Dimethylamine SCHEMBL5493029 | 0.89 | PDE2A (0.65) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5360424 | 0.86 | PDE2A (0.66) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5496998 | 0.82 | PDE2A (0.67) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4709638 | 0.81 | PDE2A (0.58) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5489020 | 0.79 | PDE2A (0.58) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5489176 | 0.78 | PDE2A (0.66) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4709075 | 0.78 | PDE2A (0.61) | PDE2AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5488783 | 0.77 | PDE2A (0.68) | PDE2AGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392663-A2 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2004-03-03 | — | — | EP | claimed |
| WO-2002098865-A2 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-12-12 | — | — | WO | claimed |