Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625524 | 0.85 | MEN1 (0.44) | CNR2CYP3A4LMNACA12CA1 | |
| SCHEMBL6624693 | 0.81 | KDM4E (0.45) | CNR2MEN1KMT2ARAB9AKDM4E | |
| Formic Acid SCHEMBL6624114 | 0.80 | CNR2 (0.36) | CNR2CYP3A4LMNACA12CA1 | |
| SCHEMBL1505647 | 0.78 | TSHR (0.54) | CYP3A4LMNAKDM4ETSHRESR1 | |
| SCHEMBL27564811 | 0.78 | CNR2 (0.36) | CNR2CYP3A4TSHRESR1TDP1 | |
| SCHEMBL6627241 | 0.77 | CNR2 (0.38) | CNR2CNR1ESR1 | |
| Iodide SCHEMBL6628988 | 0.76 | CNR2 (0.37) | CNR2 | |
| SCHEMBL16631789 | 0.74 | CYP2C9 (0.40) | CNR2CYP3A4CA12CA1CA2 | |
| SCHEMBL2405699 | 0.73 | TP53 (0.41) | CNR2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL6621875 | 0.71 | MKNK1 (0.43) | CYP3A4LMNAKMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794387-B2 | CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE (CGMP PDE5) INHIBITORS; 2-(5-ACETYL-2-BUTOXY-3-PYRIDINYL)-7-ETHYL-5-METHYLIMIDAZO(5,1 -F)(1,2,4)TRIAZIN-4(3H)-ONE FOR EXAMPLE | PFIZER INC. | 2004-09-21 | — | — | US | disclosed |
| EP-1395589-A1 | IMIDAZO-TRIAZINE DERIVATIVES AS PDE 5 INHIBITORS | Pfizer Limited (GB) | 2004-03-10 | — | — | EP | disclosed |
| EP-1380293-A1 | BONE METABOLISM IMPROVING AGENTS | The Nisshin OilliO, Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-20020177599-A1 | Pharmaceutically active compounds | PFIZER INC. | 2002-11-28 | — | — | US | disclosed |
| WO-2002079203-A1 | IMIDAZO-TRIAZINE DERIVATIVES AS PDE 5 INHIBITORS | PFIZER LIMITED (GB) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177599-A1 | Pharmaceutically active compounds | PDE5A, PDE3A, PDE2A | CNR2 1534/4885CYP3A4 432/4885LMNA 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.