Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624211 | 0.87 | PARP1 (0.68) | PARP1 | |
| SCHEMBL6626365 | 0.86 | PARP1 (0.54) | PARP1 | |
| SCHEMBL6624575 | 0.86 | PARP1 (0.53) | PARP1BRD4 | |
| SCHEMBL6624195 | 0.86 | PARP1 (0.53) | PARP1 | |
| SCHEMBL6625085 | 0.85 | PARP1 (0.72) | PARP1BRD4KDM4EALDH1A1LMNA | |
| SCHEMBL27015319 | 0.83 | PARP1 (0.79) | PARP1 | |
| SCHEMBL6625922 | 0.83 | PARP1 (0.72) | PARP1 | |
| SCHEMBL6626389 | 0.81 | PARP1 (0.49) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27015312 | 0.80 | PARP1 (0.59) | PARP1 | |
| SCHEMBL6626224 | 0.77 | PARP1 (0.49) | PARP1BRD4KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |