Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510951 | 0.88 | AVPR2 (0.66) | AVPR2 | |
| SCHEMBL6626462 | 0.79 | AVPR2 (0.77) | AVPR2 | |
| SCHEMBL5267302 | 0.79 | AVPR2 (0.68) | AVPR2 | |
| SCHEMBL6629195 | 0.77 | AVPR2 (0.66) | AVPR2 | |
| SCHEMBL6627510 | 0.77 | AVPR2 (0.67) | AVPR2 | |
| SCHEMBL6625050 | 0.74 | AVPR2 (0.68) | AVPR2 | |
| SCHEMBL6627349 | 0.74 | AVPR2 (0.49) | AVPR2 | |
| SCHEMBL5232553 | 0.73 | AVPR2 (0.68) | AVPR2 | |
| SCHEMBL5512446 | 0.73 | AVPR2 (0.66) | AVPR2 | |
| SCHEMBL5515681 | 0.73 | AVPR2 (0.68) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226122-B1 | BICYCLIC VASOPRESSIN AGONISTS | FERRING BV (NL) | 2004-12-15 | — | — | EP | claimed |
| US-6664249-B1 | Such as 1-(4-(N-(4-methoxy-4-oxobutanoyl)aminomethyl)-3-methylbenzoyl)-2, 3,4,5-tetrahydro-1H-1-benzazepine; polyuria | FERRING BV (NL) | 2003-12-16 | — | — | US | claimed |
| EP-1226122-A1 | BICYCLIC VASOPRESSIN AGONISTS | Ferring BV (NL) | 2002-07-31 | — | — | EP | claimed |
| WO-2001029005-A1 | BICYCLIC VASOPRESSIN AGONISTS | FERRING BV (NL) | 2001-04-26 | — | — | WO | claimed |
| EP-1226122-B1 | BICYCLIC VASOPRESSIN AGONISTS | FERRING BV (NL) | 2004-12-15 | — | — | EP | disclosed |
| US-6664249-B1 | Such as 1-(4-(N-(4-methoxy-4-oxobutanoyl)aminomethyl)-3-methylbenzoyl)-2, 3,4,5-tetrahydro-1H-1-benzazepine; polyuria | FERRING BV (NL) | 2003-12-16 | — | — | US | disclosed |
| EP-1226122-A1 | BICYCLIC VASOPRESSIN AGONISTS | Ferring BV (NL) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001029005-A1 | BICYCLIC VASOPRESSIN AGONISTS | FERRING BV (NL) | 2001-04-26 | — | — | WO | disclosed |