Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975728 | 0.89 | CCR8 (0.56) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6971729 | 0.83 | CCR8 (0.52) | CCR8MTNR1AMTNR1BHTR1AKCNH2 | |
| SCHEMBL6965276 | 0.82 | CCR8 (0.53) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6868975 | 0.81 | CCR8 (0.51) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6973703 | 0.81 | CCR8 (0.48) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6964570 | 0.81 | CCR8 (0.50) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6965118 | 0.81 | CCR8 (0.50) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6973699 | 0.81 | CCR8 (0.48) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL8127941 | 0.80 | CCR8 (0.49) | CCR8MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6968167 | 0.80 | CCR8 (0.49) | CCR8MTNR1AMTNR1BKCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187828-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-04-21 | — | — | EP | claimed |
| EP-1187828-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-04-21 | — | — | EP | disclosed |