Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.73 |
| ▸ | CNR2 | P34972 | 8/20 | 0.73 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | CCKAR | P32238 | 1/20 | 0.61 |
| ▸ | CCKBR | P32239 | 1/20 | 0.61 |
| ▸ | MC4R | P32245 | 1/20 | 0.61 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529012 | 1.00 | CNR1 (0.73) | CNR1CNR2ABCC4MLNRABCB11 | |
| SCHEMBL31528968 | 0.96 | CNR1 (0.70) | CNR1CNR2ABCC4MLNRABCB11 | |
| SCHEMBL12064370 | 0.93 | CNR1 (0.73) | CNR1CNR2ABCC4MLNRABCB11 | |
| SCHEMBL31528990 | 0.93 | CNR1 (0.73) | CNR1CNR2ABCC4MLNRABCB11 | |
| SCHEMBL31528972 | 0.93 | CNR1 (0.83) | CNR1CNR2ABCC4MLNRABCB11 | |
| SCHEMBL662139 | 0.92 | CNR1 (0.68) | CNR1CNR2CYP2C9GPR55 | |
| SCHEMBL31529019 | 0.92 | CNR1 (0.68) | CNR1CNR2CYP2C9GPR55 | |
| SCHEMBL31529009 | 0.92 | CNR1 (0.73) | CNR1CNR2ABCC4MLNRABCB11 | |
| SCHEMBL662097 | 0.92 | CNR1 (0.84) | CNR1CNR2ABCC4MLNRABCB11 | |
| SCHEMBL31528964 | 0.92 | CNR1 (0.75) | CNR1CNR2ABCC4MLNRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853205-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853205-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | UNIVERSITY OF CONNECTICUT | 2012-02-23 | — | — | US | disclosed |
| WO-2010104488-A1 | NOVEL HETERO PYRROLE ANALOGS ACTING ON CANNAPINOID RECEPTORS | UNIVERSITY OF CONNECTICUT (US) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | CNR1, CNR2, CBR3 | CNR1 1/4885CNR2 2/4885ABCC4 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.