Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669350 | 1.00 | PIM2 (0.44) | PIM2HDAC4TDP1LDHALDHB | |
| SCHEMBL6669344 | 1.00 | PIM2 (0.44) | PIM2HDAC4TDP1LDHALDHB | |
| SCHEMBL6669339 | 1.00 | PIM2 (0.44) | PIM2HDAC4TDP1LDHALDHB | |
| SCHEMBL30795152 | 1.00 | PIM2 (0.44) | PIM2HDAC4TDP1LDHALDHB | |
| SCHEMBL6624883 | 0.89 | TDP1 (0.44) | TDP1 | |
| SCHEMBL6672823 | 0.89 | TDP1 (0.44) | TDP1 | |
| SCHEMBL6672826 | 0.89 | TDP1 (0.44) | TDP1 | |
| SCHEMBL6672822 | 0.89 | TDP1 (0.44) | TDP1 | |
| SCHEMBL6670254 | 0.87 | TDP1 (0.44) | TDP1 | |
| SCHEMBL30824689 | 0.87 | TDP1 (0.44) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392644-A1 | CINNAMIDE DERIVATIVES AS KCNQ POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-03-03 | — | — | EP | claimed |
| WO-2002096858-A1 | CINNAMIDE DERIVATIVES AS KCNQ POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-12-05 | — | — | WO | claimed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |