Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628018 | 1.00 | ADORA2A (0.62) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL6626068 | 0.86 | ADORA2A (0.61) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL6626073 | 0.86 | ADORA2A (0.61) | ADORA2AADORA1 | |
| SCHEMBL6628558 | 0.82 | ADORA2A (0.57) | ADORA2AADORA1 | |
| SCHEMBL6628570 | 0.82 | ADORA2A (0.57) | ADORA2AADORA1 | |
| SCHEMBL6629182 | 0.81 | ADORA2A (0.56) | ADORA2AADORA1 | |
| SCHEMBL6629185 | 0.81 | ADORA2A (0.56) | ADORA2AADORA1 | |
| SCHEMBL6625642 | 0.81 | ADORA2A (0.66) | ADORA2AADORA1 | |
| SCHEMBL6196510 | 0.81 | ADORA2A (0.63) | ADORA2AADORA1 | |
| SCHEMBL6622137 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976753-B1 | [1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-6222035-B1 | AS ADENOSINE A.SUB.2A RECEPTOR ANTAGONISTS AND ARE USEFUL FOR THERAPY OR OR PROPHYLAXIS OF VARIOUS DISEASES INDUCED BY HYPERACTIVITY OF ADENOSINE A.SUB.2A RECEPTORS SUCH AS PARKINSON'S DISEASE, SENILE DEMENTIA OR DEPRESSION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0976753-A1 | [1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |