Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.89 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.73 |
| ▸ | CDK1 | P06493 | 1/20 | 0.71 |
| ▸ | CDK2 | P24941 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460297 | 0.94 | GSK3B (1.00) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL1461692 | 0.92 | GSK3B (0.84) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL6487527 | 0.91 | GSK3B (0.86) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL6478233 | 0.87 | GSK3B (0.80) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL6489278 | 0.86 | GSK3B (0.76) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL1461361 | 0.85 | GSK3B (1.00) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL31061079 | 0.85 | GSK3B (1.00) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL1461539 | 0.85 | GSK3B (0.77) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL1461347 | 0.84 | GSK3B (1.00) | GSK3BCYP1A2CDK1CDK2 | |
| SCHEMBL1461522 | 0.84 | GSK3B (0.77) | GSK3BCYP1A2CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487804-A2 | AMINOINDAZOLE DERIVATIVES AS PROTEIN-KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078403-A2 | DERIVES D’AMINOINDAZOLES COMME INHIBITEURS DE PROTEINE-KINASE | AVENTIS PHARMA S.A. (FR) | 2003-09-25 | — | — | WO | disclosed |