2,4-Dichlorophenoxyacetic Acid

2,4-Dichlorophenoxyacetic Acid

SCHEMBL6629319

CCC(CC)CC.CCC(CC)CC.CCC(CC)CC.O=C(O)COc1ccc(Cl)cc1Cl.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.61
TSHR P16473 2/20 0.60
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
MITF O75030 1/20 0.54
TP53 P04637 1/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
XBP1 P17861 1/20 0.54
PTGDR2 Q9Y5Y4 5/20 0.52
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
MAPK1 P28482 1/20 0.50
POLB P06746 1/20 0.50
HTT P42858 1/20 0.50
GAA P10253 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
KDM4E B2RXH2 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenoxyacetic Acid SCHEMBL6626890 0.87 TDP1 (0.56) TDP1TSHRRAB9ANPC1MITF
Triphenylphosphine Oxide SCHEMBL6626923 0.83 TDP1 (0.63) TDP1TSHRPTGDR2ALDH1A1MAPK1
2,4-Dichlorophenoxyacetic Acid SCHEMBL23242752 0.81 TDP1 (0.93) TDP1TSHRPTGDR2ALDH1A1LMNA
SCHEMBL12147402 0.79 PTGDR2 (0.68) TDP1TSHRRAB9ANPC1MITF
2,4-Dichlorophenoxyacetic Acid SCHEMBL6630230 0.79 TDP1 (0.57) TDP1TSHRPTGDR2ALDH1A1MAPK1
2,4-Dichlorophenoxyacetic Acid SCHEMBL6627168 0.79 TDP1 (0.57) TDP1TSHRPTGDR2ALDH1A1MAPK1
2,4-Dichlorophenoxyacetic Acid SCHEMBL6628716 0.79 TDP1 (0.57) TDP1TSHRHPGDPTGDR2ALDH1A1
2,4-Dichlorophenoxyacetic Acid SCHEMBL226803 0.78 TDP1 (1.00) TDP1TSHRHPGDPTGDR2HTT
2,4-Dichlorophenoxyacetic Acid SCHEMBL31108925 0.78 TDP1 (1.00) TDP1TSHRHPGDPTGDR2HTT
2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 0.78 TDP1 (1.00) TDP1TSHRHPGDPTGDR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1417279-A2 TRIBOLUMINESCENT MATERIALS AND DEVICES CONTAINING THEM Qinetiq Limited (GB) 2004-05-12 EP disclosed
WO-2003016428-A2 TRIBOLUMINESCENT MATERIALS AND DEVICES CONTAINING THEM QINETIQ LIMITED (GB) 2003-02-27 WO disclosed