Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628875 | 1.00 | TTR (0.44) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL6628876 | 1.00 | TTR (0.44) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL6627847 | 0.81 | TTR (0.41) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL6628482 | 0.73 | SMN1; SMN2 (0.46) | DPP4SMN1; SMN2NPC1PKM | |
| SCHEMBL963057 | 0.72 | CA12 (0.57) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL963055 | 0.72 | CA12 (0.57) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL9315134 | 0.71 | TTR (0.46) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL29709927 | 0.70 | TTR (0.43) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL12644866 | 0.70 | TTR (0.48) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL12681711 | 0.70 | SMN1; SMN2 (0.51) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301517-B1 | THIENOPYRROLIDINONES | HOFFMANN LA ROCHE (CH) | 2004-12-15 | — | — | EP | disclosed |